RESUMO
BACKGROUND: Several studies support the hypothesis that scabies is on the rise in Spain. There are also concerns about the possible development of resistance to treatment and an increase in atypical presentations. The aims of this study were to describe the demographic and clinical characteristics of patients with scabies seen by dermatologists in Spain, to identify the possible emergence of atypical forms of scabies, and to explore the frequency of treatment failures and associated risk factors. METHODS: We conducted an observational, cross-sectional, multicenter study of data collected prospectively in April and May 2023 using the CLINI-AEDVp platform created by the Spanish Academy of Dermatology and Venereology (AEDV). RESULTS: Participating dermatologists from 31 hospitals in 15 of Spain's autonomous communities recorded 186 cases of active scabies (51% in women) during the study period. A diagnostic certainty level of A, B or C as per the International Alliance for the Control of Scabies Consensus Criteria was required for diagnosis. Overall, 92% of patients had typical scabies and 66% had already been treated with a scabicide for the current episode. Of the treated patients, only 36% had received and completed adequate treatment (including the simultaneous treatment of all household members) and 50% had not received clear written recommendations. CONCLUSIONS: In a high proportion of the cases of scabies studied, the patient had already received treatment. In those cases, we observed several remediable shortcomings that could explain why some of these treatments had failed. Remedying these deficiencies should lead to better control of scabies and an improved assessment of the actual effectiveness of currently available scabicides.
Assuntos
Escabiose , Humanos , Feminino , Escabiose/tratamento farmacológico , Escabiose/epidemiologia , Espanha/epidemiologia , Estudos Transversais , Falha de Tratamento , Academias e InstitutosRESUMO
BACKGROUND: Several studies support the hypothesis that scabies is on the rise in Spain. There are also concerns about the possible development of resistance to treatment and an increase in atypical presentations. The aims of this study were to describe the demographic and clinical characteristics of patients with scabies seen by dermatologists in Spain, to identify the possible emergence of atypical forms of scabies, and to explore the frequency of treatment failures and associated risk factors. METHODS: We conducted an observational, cross-sectional, multicenter study of data collected prospectively in April and May 2023 using the CLINI-AEDVp platform created by the Spanish Academy of Dermatology and Venereology (AEDV). RESULTS: Participating dermatologists from 31 hospitals in 15 of Spain's autonomous communities recorded 186 cases of active scabies (51% in women) during the study period. A diagnostic certainty level of A, B or C as per the International Alliance for the Control of Scabies Consensus Criteria was required for diagnosis. Overall, 92% of patients had clinical features of classic scabies and 66% had already been treated with a scabicide for the current episode. Of the treated patients, only 36% had received and completed adequate treatment (including the simultaneous treatment of all household members) and 50% had not received clear written recommendations. CONCLUSIONS: In a high proportion of scabies cases, the patient has already received treatment. In those cases, we observe several remediable shortcomings that could explain why some of these treatments fail. Remedying these deficiencies should lead to better control of scabies and an improved assessment of the actual effectiveness of currently available scabicides.
Assuntos
Escabiose , Humanos , Feminino , Escabiose/diagnóstico , Escabiose/tratamento farmacológico , Escabiose/epidemiologia , Espanha/epidemiologia , Estudos Transversais , Falha de Tratamento , Academias e InstitutosAssuntos
Dermatoses Faciais/diagnóstico por imagem , Granuloma/diagnóstico por imagem , Ultrassonografia Doppler , Abscesso/diagnóstico , Pré-Escolar , Diagnóstico Diferencial , Cisto Epidérmico/diagnóstico , Granuloma Piogênico/diagnóstico , Humanos , Masculino , Pioderma/diagnóstico por imagem , Remissão EspontâneaRESUMO
Twenty-four male Mexican hairless pigs, weighing 16 ± 1.12 kg, were used to evaluate growth performance and carcass yield in pigs fed 2 (L), 3 (M) and 4 (H) times the Metabolizable Energy (ME) required for maintenance. The pigs were assigned randomly to two experimental rearing systems (indoors and outdoors). They were fed daily according to their respective feeding regimen (FR). The indoor pigs were fed ad libitum with chopped star grass forage (Cynodon nlemfuensis). The outdoor pigs had access during 16 h to a paddock of star grass. The pigs were slaughtered when they achieve 70 kg of live weight. No significant differences between indoors and outdoors were observed in any of the variables evaluated (P > 0.05). A significant reduction of daily live weight gain (P < 0.05) was observed conforming to FR reductions (0.501, 0.438 and 0.300 kg/day for H, M and L, respectively). Days to achieve 70 kg of live weight increase (P < 0.05) as FR reduces (110, 124 and 180 days for H, M and L, respectively) were recorded. Forage consumption in pigs reared indoors reduces (P < 0.05) conforming to FR increases (0.092, 0.121 and 0.307 kg DM/day for H, M and L respectively). Fat carcass yield reduces significantly (P < 0.05) according FR reductions (24.5, 22.8 y 18.9 kg, for H, M and L respectively). Also, carcass meat yield was higher (P < 0.05) in pigs from L regimen (25.0 kg) than in pigs from M and H regimen (22.0 and 22.8 kg, respectively). Results obtained indicate a reduction in daily live weight gain conforming to daily feed intake reductions; however, improvement in carcass meat yield, accompanied with a reduction in carcass fat yield, was observed.
Assuntos
Ração Animal , Criação de Animais Domésticos , Suínos/fisiologia , Animais , Composição Corporal , Metabolismo Energético , Masculino , Carne/normas , México , Suínos/crescimento & desenvolvimento , Aumento de PesoAssuntos
Hepatite C Crônica/tratamento farmacológico , Interferon-alfa/efeitos adversos , Transtornos da Pigmentação/induzido quimicamente , Polietilenoglicóis/efeitos adversos , Ribavirina/efeitos adversos , Língua/patologia , Adulto , Feminino , Humanos , Interferon alfa-2 , Interferon-alfa/administração & dosagem , Interferon-alfa/uso terapêutico , Polietilenoglicóis/administração & dosagem , Polietilenoglicóis/uso terapêutico , Proteínas Recombinantes , Ribavirina/administração & dosagem , Ribavirina/uso terapêutico , População BrancaRESUMO
INTRODUCTION: Up to 30% of squamous cell carcinomas of the penis arise from a lichen sclerosus, but very few reports in which lichen planus was the preexisting lesion have been published. We report a male with verrucous carcinoma of penis that developed in an area of lichen planus. CLINICAL CASE: A 53-year-old male presented with an exophytic tumor on the glans penis that had been present for about 6 months. The lesion developed in a previously biopsied area of lichen planus hypertrophicus. After excision, histological diagnosis was verrucous carcinoma. COMMENT: The development of any subtype of squamous cell carcinoma of penis in a lichen planus can be coincidental, or a neoplastic transformation of lichen planus can take place.
Assuntos
Carcinoma Verrucoso/patologia , Líquen Plano/patologia , Síndromes Paraneoplásicas/patologia , Doenças do Pênis/patologia , Neoplasias Penianas/patologia , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The existence of a group of insect of medical importance belonging to the families Culicidae, Blattide, Muscidae, Tabanidae, Ceratopogonidae and Chloropidae was reported in the northwestern keys of Camagüey (keys Mégano Grande, Cruz, Romano and Güajaba). Key Romano seems to have the best ecological conditions for the establishment of such vectors according to the number of species reported.